Drug

Who makes adapalene?

9 companies list adapalene as a human prescription drug, including under the names DIFFERIN. Forms: cream; gel; swab. Routes: topical.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing adapalene

CompanyFormsApplicationNDCsRegistered sites
Alembic Pharmaceuticals LimitedIndiagelANDAANDA21350827
Bryant Ranch PrepackUnited StatescreamANDAANDA09082421
Sun Pharmaceutical Industries LimitedIndiagelANDAANDA208322113
Padagis Israel Pharmaceuticals LtdUnited StatescreamNDA AUTHORIZED GENERICNDA02074812
Actavis LLCUnited StatesgelANDAANDA20100011
CALL INC. (dba Rochester Pharmaceuticals)swabANDAANDA20459310
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLCcreamANDAANDA09082410
Galderma Laboratories, L.P.gelNDANDA02175310
Mayne Pharma Commercial LLC.gelNDA AUTHORIZED GENERICNDA02175310

Bulk ingredient listings

Orange Book patents

1 unexpired patent lists adapalene as the active ingredient, expiring between May 2028 and May 2028. Application holder: GALDERMA LABORATORIES LP.

Enquiry

Common questions

Who makes adapalene?
9 companies list adapalene as a human prescription drug in the openFDA NDC Directory, led by Alembic Pharmaceuticals Limited, Bryant Ranch Prepack, Sun Pharmaceutical Industries Limited, Padagis Israel Pharmaceuticals Ltd, Actavis LLC. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic DIFFERIN?
6 companies list adapalene under an abbreviated new drug application (ANDA), the application type used for generics, and 1 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies adapalene active ingredient?
10 companies list adapalene as a bulk ingredient, including AARTI PHARMALABS LIMITED, Alivus Life Sciences Limited, Arch Pharmalabs Limited, Chongqing Huapont Shengchem Pharmaceutical Co., Ltd..