Drug

Who makes bupivacaine?

2 companies list bupivacaine as a human prescription drug, including under the names EXPAREL. Forms: injection, suspension, liposomal. Routes: infiltration.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing bupivacaine

CompanyFormsApplicationNDCsRegistered sites
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Chinainjection, suspension, liposomalANDAANDA21434824
Pacira Pharmaceuticals, Inc.United Statesinjection, suspension, liposomalNDANDA02249621

Bulk ingredient listings

Orange Book patents

23 unexpired patents list bupivacaine as the active ingredient, expiring between Jan 2041 and Jul 2044. Application holders: INNOCOLL PHARMACEUTICALS LTD, PACIRA PHARMACEUTICALS INC.

Enquiry

Common questions

Who makes bupivacaine?
2 companies list bupivacaine as a human prescription drug in the openFDA NDC Directory, led by Jiangsu Hengrui Pharmaceuticals Co., Ltd., Pacira Pharmaceuticals, Inc.. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic EXPAREL?
1 company lists bupivacaine under an abbreviated new drug application (ANDA), the application type used for generics, and 1 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies bupivacaine active ingredient?
4 companies list bupivacaine as a bulk ingredient, including Jiangsu Hengrui Pharmaceuticals Co., Ltd., MSN Life Sciences Private Limited, Nortec Quimica SA, Siegfried Evionnaz SA.