Drug

Who makes bupivacaine hydrochloride and epinephrine?

2 companies list bupivacaine hydrochloride and epinephrine as a human prescription drug, including under the names Marcaine with Epinephrine. Forms: injection, solution. Routes: epidural, infiltration, intracaudal, perineural.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing bupivacaine hydrochloride and epinephrine

CompanyFormsApplicationNDCsRegistered sites
Hospira, Inc.United Statesinjection, solutionANDA, NDAANDA071165, ANDA071167, ANDA071168107
Henry Schein, Inc.United Statesinjection, solutionANDAANDA07116511
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Common questions

Who makes bupivacaine hydrochloride and epinephrine?
2 companies list bupivacaine hydrochloride and epinephrine as a human prescription drug in the openFDA NDC Directory, led by Hospira, Inc., Henry Schein, Inc.. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic Marcaine with Epinephrine?
2 companies list bupivacaine hydrochloride and epinephrine under an abbreviated new drug application (ANDA), the application type used for generics, and 1 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.