Drug

Who makes bupivacaine hydrochloride and epinephrine bitartrate?

5 companies list bupivacaine hydrochloride and epinephrine bitartrate as a human prescription drug, including under the names Marcaine with Epinephrine, SENSORCAINE, SENSORCAINE MPF, Marcaine, Vivacaine. Forms: injection, solution. Routes: epidural, infiltration, intracaudal, perineural, retrobulbar, submucosal.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing bupivacaine hydrochloride and epinephrine bitartrate

CompanyFormsApplicationNDCsRegistered sites
Fresenius Kabi USA, LLCUnited Statesinjection, solutionANDA, NDAANDA070966, ANDA070967, ANDA07096856
Hospira, Inc.United Statesinjection, solutionNDANDA01696447
Septodont SASFranceinjection, solutionANDAANDA07725021
Henry Schein, Inc.United Statesinjection, solutionNDANDA01696411
Sportpharm LLCinjection, solutionANDAANDA07096810
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Common questions

Who makes bupivacaine hydrochloride and epinephrine bitartrate?
5 companies list bupivacaine hydrochloride and epinephrine bitartrate as a human prescription drug in the openFDA NDC Directory, led by Fresenius Kabi USA, LLC, Hospira, Inc., Septodont SAS, Henry Schein, Inc., Sportpharm LLC. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic Marcaine with Epinephrine?
3 companies list bupivacaine hydrochloride and epinephrine bitartrate under an abbreviated new drug application (ANDA), the application type used for generics, and 3 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.