Drug

Who makes chlorhexidine gluconate?

22 companies list chlorhexidine gluconate as a human prescription drug, including under the names ANTISEPTIC SKIN CLEANSER, Peridex, Periogard Alcohol Free, Sky Oral Rinse. Forms: liquid; rinse; solution. Routes: buccal, dental, oral, topical.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing chlorhexidine gluconate

CompanyFormsApplicationNDCsRegistered sites
Xttrium Laboratories, Inc.United Statesliquid; rinse; solutionANDA, NDAANDA077789, NDA01912582
PAI Holdings, LLCUnited StatesrinseANDAANDA07452221
South Atlantic Corporation LLCUnited StatesrinseANDAANDA077789, ANDA20321221
Colgate Oral Pharmaceuticals, Inc.rinseANDAANDA20321220
Medline Industries, LPUnited StatesrinseANDAANDA07778915
International Medication Systems, Ltd.United StatesrinseANDAANDA07778913
Sage Pharmaceuticals IncUnited StatesliquidANDAANDA07778912
Solventum CorporationUnited StatesrinseNDANDA01902812
Den-Mat Holdings, LLCUnited StatesrinseANDAANDA07778911
Lyne Laboratories, Inc.United StatesrinseANDAANDA07429111
NuCare Pharmaceuticals,Inc.United StatesrinseANDAANDA07778911
Preferred Pharmaceuticals Inc.United StatesrinseANDAANDA07778911
Proficient Rx LPUnited StatesrinseANDAANDA07778911
RemedyRepack, IncUnited StatesrinseANDAANDA07778911
Atlantic Biologicals Corps.rinseANDAANDA07778910
Benco DentalrinseANDAANDA07778910
Darby Dental Supply, LLCrinseANDAANDA07778910
Dentsply LLC. Professional Division Trading as "DENTSPLY Professional"rinseANDAANDA07778910
MAJOR Pharmaceuticals Inc.rinseANDAANDA07778910
Mckesson Corporation DBA SKY PackaginngrinseANDAANDA07778910
Safco Dental Supply Co.solutionANDAANDA07556110
VistaPharm, LLCrinseANDAANDA20321210

Bulk ingredient listings

Orange Book patents

1 unexpired patent lists chlorhexidine gluconate as the active ingredient, expiring between Oct 2027 and Oct 2027. Application holder: SAGE PRODUCTS INC.

Enquiry

Common questions

Who makes chlorhexidine gluconate?
22 companies list chlorhexidine gluconate as a human prescription drug in the openFDA NDC Directory, led by Xttrium Laboratories, Inc., PAI Holdings, LLC, South Atlantic Corporation LLC, Colgate Oral Pharmaceuticals, Inc., Medline Industries, LP. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic ANTISEPTIC SKIN CLEANSER?
21 companies list chlorhexidine gluconate under an abbreviated new drug application (ANDA), the application type used for generics, and 2 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies chlorhexidine gluconate active ingredient?
5 companies list chlorhexidine gluconate as a bulk ingredient, including AVA Inc., DISHMAN CARBOGEN AMCIS LIMITED, MEDISCA Inc., Professional Compounding Centers of America dba PCCA.