Drug

Who makes macitentan?

14 companies list macitentan as a human prescription drug, including under the names OPSUMIT. Forms: tablet; tablet, film coated. Routes: oral.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing macitentan

CompanyFormsApplicationNDCsRegistered sites
Alembic Pharmaceuticals LimitedIndiatablet, film coatedANDAANDA21112827
Sun Pharmaceutical Industries LimitedIndiatablet, film coatedANDAANDA211123113
Apotex Inc.Canadatablet, film coatedANDAANDA21119516
Aurobindo Pharma LimitedIndiatablet, film coatedANDAANDA21119816
Teva Pharmaceutical Industries Ltd.Canadatablet, film coatedANDAANDA21118716
LAURUS LABS LIMITEDIndiatablet, film coatedANDAANDA21112015
Sandoz Industrial Products S.AAustriatablet, film coatedANDAANDA21113615
Torrent Pharma, Inc.IndiatabletANDAANDA21110715
Excella GmbH & Co. KGGermanytablet, film coatedDRUG FOR FURTHER PROCESSING11
Novugen Pharma Sdn. Bhd.Malaysiatablet, film coatedANDAANDA21102611
Zydus Pharmaceuticals USA Inc.Indiatablet, film coatedANDAANDA21122411
Actelion Pharmaceuticals US, Inc.tablet, film coatedNDANDA20441010
Amneal Pharmaceuticals NY LLCtablet, film coatedANDAANDA21100010
Mylan Pharmaceuticals, Inc.tablet, film coatedANDAANDA21116110

Bulk ingredient listings

Orange Book patents

7 unexpired patents list macitentan as the active ingredient, expiring between Mar 2027 and Oct 2029. Application holder: ACTELION PHARMACEUTICALS US INC.

Enquiry

Common questions

Who makes macitentan?
14 companies list macitentan as a human prescription drug in the openFDA NDC Directory, led by Alembic Pharmaceuticals Limited, Sun Pharmaceutical Industries Limited, Apotex Inc., Aurobindo Pharma Limited, Teva Pharmaceutical Industries Ltd.. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic OPSUMIT?
12 companies list macitentan under an abbreviated new drug application (ANDA), the application type used for generics, and 1 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies macitentan active ingredient?
8 companies list macitentan as a bulk ingredient, including Zhejiang Ausun Pharmaceutical Co., Ltd., Aurobindo Pharma Limited, Honour Lab Limited, MSN Life Sciences Private Limited.