Drug

Who makes oxymetazoline hydrochloride?

3 companies list oxymetazoline hydrochloride as a human prescription drug, including under the names Rhofade. Forms: cream. Routes: topical.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing oxymetazoline hydrochloride

CompanyFormsApplicationNDCsRegistered sites
Mayne Pharma International Pty Ltd.AustraliacreamNDANDA20855221
Sun Pharmaceutical Industries LimitedIndiacreamANDAANDA213584113
EPI Health, LLCcreamNDANDA20855210

Bulk ingredient listings

Orange Book patents

21 unexpired patents list oxymetazoline hydrochloride as the active ingredient, expiring between May 2028 and Dec 2039. Application holders: MAYNE PHARMA LLC, RVL PHARMACEUTICALS INC.

Enquiry

Common questions

Who makes oxymetazoline hydrochloride?
3 companies list oxymetazoline hydrochloride as a human prescription drug in the openFDA NDC Directory, led by Mayne Pharma International Pty Ltd., Sun Pharmaceutical Industries Limited, EPI Health, LLC. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic Rhofade?
1 company lists oxymetazoline hydrochloride under an abbreviated new drug application (ANDA), the application type used for generics, and 2 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies oxymetazoline hydrochloride active ingredient?
6 companies list oxymetazoline hydrochloride as a bulk ingredient, including CTX Lifesciences Pvt. Ltd., LETCO MEDICAL, LLC, Professional Compounding Centers of America dba PCCA, SHODHANA LABORATORIES PRIVATE LIMITED.