Drug

Who makes pioglitazone and metformin hydrochloride?

3 companies list pioglitazone and metformin hydrochloride as a human prescription drug, including under the names Actoplus Met. Forms: tablet; tablet, film coated. Routes: oral.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing pioglitazone and metformin hydrochloride

CompanyFormsApplicationNDCsRegistered sites
Macleods Pharmaceuticals LimitedIndiatabletANDAANDA20480225
Bryant Ranch PrepackUnited StatestabletANDAANDA20480221
Takeda Pharmaceuticals U.S.A., Inc.Germanytablet, film coatedNDANDA02184217
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Common questions

Who makes pioglitazone and metformin hydrochloride?
3 companies list pioglitazone and metformin hydrochloride as a human prescription drug in the openFDA NDC Directory, led by Macleods Pharmaceuticals Limited, Bryant Ranch Prepack, Takeda Pharmaceuticals U.S.A., Inc.. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic Actoplus Met?
2 companies list pioglitazone and metformin hydrochloride under an abbreviated new drug application (ANDA), the application type used for generics, and 1 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.