Drug

Who makes sitagliptin and metformin hydrochloride?

8 companies list sitagliptin and metformin hydrochloride as a human prescription drug, including under the names JANUMET, JANUMET XR, ZITUVIMET, ZITUVIMET XR. Forms: tablet, film coated; tablet, film coated, extended release. Routes: oral.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing sitagliptin and metformin hydrochloride

CompanyFormsApplicationNDCsRegistered sites
Zydus Lifesciences LimitedIndiatablet, film coated; tablet, film coated, extended releaseNDA, NDA AUTHORIZED GENERICNDA216743, NDA2167781012
Zydus Pharmaceuticals USA Inc.Indiatablet, film coated; tablet, film coated, extended releaseNDA, NDA AUTHORIZED GENERICNDA216743, NDA216778101
Merck Sharp & Dohme Corp.tablet, film coated; tablet, film coated, extended releaseNDANDA022044, NDA20227050
Par Health USA, LLCIndiatablet, film coated, extended releaseANDAANDA20414435
International Medication Systems, Ltd.United Statestablet, film coated; tablet, film coated, extended releaseNDANDA022044, NDA20227033
Apotex Inc.Canadatablet, film coatedANDAANDA20242626
Sandoz Industrial Products S.AAustriatablet, film coatedANDAANDA20238825
Golden State Medical Supply Inc.United Statestablet, film coatedANDAANDA20242621
Enquiry

Common questions

Who makes sitagliptin and metformin hydrochloride?
8 companies list sitagliptin and metformin hydrochloride as a human prescription drug in the openFDA NDC Directory, led by Zydus Lifesciences Limited, Zydus Pharmaceuticals USA Inc., Merck Sharp & Dohme Corp., Par Health USA, LLC, International Medication Systems, Ltd.. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic JANUMET?
4 companies list sitagliptin and metformin hydrochloride under an abbreviated new drug application (ANDA), the application type used for generics, and 4 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.