Drug

Who makes buprenorphine?

22 companies list buprenorphine as a human prescription drug, including under the names BRIXADI, Butrans, SUBLOCADE. Forms: injection; patch; patch, extended release; solution; tablet. Routes: subcutaneous, sublingual, transdermal.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing buprenorphine

CompanyFormsApplicationNDCsRegistered sites
Braeburn Inc.injectionNDANDA21013670
Rhodes Pharmaceuticals LLCpatch; tabletANDA, NDA AUTHORIZED GENERICANDA207276, NDA02130670
Bryant Ranch PrepackUnited StatestabletANDAANDA201760, ANDA20727661
Teva Pharmaceutical Industries Ltd.Canadapatch, extended releaseANDAANDA20493756
Aveva Drug Delivery Systems Inc.United Statespatch, extended releaseANDAANDA21027251
Knoa Pharma LLCUnited Statespatch, extended releaseNDANDA02130651
Amneal Pharmaceuticals NY LLCpatch, extended releaseANDAANDA21158650
Ingenus Pharmaceuticals, LLCpatch, extended releaseANDAANDA21027250
CLINICAL SOLUTIONS WHOLESALE, LLCUnited StatestabletANDAANDA201760, ANDA20727641
Alvogen, Inc.patch, extended releaseANDAANDA20749040
Sun Pharmaceutical Industries LimitedIndiatabletANDAANDA201760213
Pharma Packaging Solutions, LLC dba Tjoapack, LLCUnited StatestabletANDAANDA20727625
Hikma Pharmaceuticals USA Inc.United StatestabletANDAANDA07863324
Indivior Inc.United StatessolutionNDANDA20981922
Actavis LLCUnited StatestabletANDAANDA09081921
Unit Dose Solutions, Inc.United StatestabletANDAANDA20727621
AvPAKtabletANDAANDA20176020
MAJOR Pharmaceuticals Inc.tabletANDAANDA07863320
International Medication Systems, Ltd.United StatestabletANDAANDA20727613
LTS Therapy Systems, LLCUnited Statespatch, extended releaseANDAANDA20749013
RedPharm DrugUnited StatestabletANDAANDA20176011
RemedyRepack, IncUnited StatestabletANDAANDA09081911

Bulk ingredient listings

Orange Book patents

20 unexpired patents list buprenorphine as the active ingredient, expiring between Jan 2027 and Jun 2038. Application holders: BRAEBURN INC, INDIVIOR INC.

Enquiry

Common questions

Who makes buprenorphine?
22 companies list buprenorphine as a human prescription drug in the openFDA NDC Directory, led by Braeburn Inc., Rhodes Pharmaceuticals LLC, Bryant Ranch Prepack, Teva Pharmaceutical Industries Ltd., Aveva Drug Delivery Systems Inc.. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic BRIXADI?
19 companies list buprenorphine under an abbreviated new drug application (ANDA), the application type used for generics, and 3 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies buprenorphine active ingredient?
14 companies list buprenorphine as a bulk ingredient, including Arevipharma GmbH, Indivior Inc., Janssen Pharmaceuticals Sciences Unlimited Company, Janssen Pharmaceuticals, Inc..