Drug

Who makes diphenoxylate hydrochloride and atropine sulfate?

20 companies list diphenoxylate hydrochloride and atropine sulfate as a human prescription drug, including under the names Lomotil. Forms: solution; tablet. Routes: oral.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing diphenoxylate hydrochloride and atropine sulfate

CompanyFormsApplicationNDCsRegistered sites
Aphena Pharma Solutions - Tennessee, LLCtabletANDA, NDA AUTHORIZED GENERICANDA086727, ANDA213335, ANDA21341340
International Medication Systems, Ltd.United StatestabletANDAANDA086727, ANDA21341333
Bryant Ranch PrepackUnited StatestabletANDAANDA086727, ANDA21341321
Proficient Rx LPUnited StatestabletANDAANDA086727, ANDA21341321
RedPharm DrugUnited StatestabletANDAANDA21341321
Pharma Packaging Solutions, LLC dba Tjoapack, LLCUnited StatestabletANDAANDA21333515
SpecGx LLCUnited StatestabletANDAANDA21333515
Unichem Laboratories Limited, IndiaIndiatabletANDAANDA21081915
Hikma Pharmaceuticals USA Inc.United StatessolutionANDAANDA08770814
ANI Pharmaceuticals, Inc.United StatestabletANDAANDA08672711
Direct RxUnited StatestabletANDAANDA21341311
Leading Pharma, LLCUnited StatestabletANDAANDA21341311
NuCare Pharmaceuticals,Inc.United StatestabletANDAANDA08672711
PD-Rx Pharmaceuticals Inc.United StatestabletANDAANDA21341311
Preferred Pharmaceuticals Inc.United StatestabletANDAANDA21341311
RemedyRepack, IncUnited StatestabletANDAANDA21341311
WINDER LABORATORIES, LLCUnited StatestabletANDAANDA21136211
Chartwell RX, LLC.tabletANDAANDA20712810
Mylan Pharmaceuticals, Inc.tabletNDA AUTHORIZED GENERICNDA01246210
Pfizer Laboratories Div Pfizer InctabletNDANDA01246210

Bulk ingredient listings

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Common questions

Who makes diphenoxylate hydrochloride and atropine sulfate?
20 companies list diphenoxylate hydrochloride and atropine sulfate as a human prescription drug in the openFDA NDC Directory, led by Aphena Pharma Solutions - Tennessee, LLC, International Medication Systems, Ltd., Bryant Ranch Prepack, Proficient Rx LP, RedPharm Drug. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic Lomotil?
18 companies list diphenoxylate hydrochloride and atropine sulfate under an abbreviated new drug application (ANDA), the application type used for generics, and 1 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies diphenoxylate hydrochloride and atropine sulfate active ingredient?
1 company lists diphenoxylate hydrochloride and atropine sulfate as a bulk ingredient, including KALINTIS HEALTHCARE PRIVATE LIMITED.