Drug

Who makes tacrolimus?

35 companies list tacrolimus as a human prescription drug, including under the names Envarsus XR, Prograf. Forms: capsule; capsule, extended release; capsule, gelatin coated; granule, for suspension; injection; injection, solution; ointment; tablet, extended release. Routes: intravenous, oral, topical.

Labellers from the openFDA NDC Directory. A labeller is the firm named on the label, not necessarily the site that made the product, and a listing is not an FDA approval. Data as of 24 Sept 2026. Methodology

Companies listing tacrolimus

CompanyFormsApplicationNDCsRegistered sites
Astellas Pharma US, Inc.Japancapsule, gelatin coated; granule, for suspension; injection, solutionNDANDA050708, NDA050709, NDA21011568
Bryant Ranch PrepackUnited StatescapsuleANDAANDA065461, ANDA09119561
Glenmark Pharmaceuticals Inc., USAIndiacapsule; ointmentANDAANDA206662, ANDA21039359
ACCORD HEALTHCARE LIMITEDUnited Kingdomcapsule; ointmentANDAANDA091195, ANDA21168852
Dr. Reddy's Laboratories LimitedIndiacapsuleANDAANDA090509315
Biocon Biologics LimitedIndiacapsuleANDAANDA21229739
Pharma Packaging Solutions, LLC dba Tjoapack, LLCUnited StatescapsuleANDAANDA09050935
Sandoz Industrial Products S.AAustriacapsuleANDAANDA06546135
Strides Pharma Science LimitedIndiacapsuleANDAANDA09068735
Concord Biotech LimitedIndiacapsuleANDAANDA21311233
Safecor Health, LLCUnited StatescapsuleANDAANDA09059633
AJENAT PHARMACEUTICALS LLCUnited StatescapsuleANDAANDA20665132
BPI Labs, DBA Ally LabsUnited StatescapsuleANDAANDA20665132
Golden State Medical Supply Inc.United StatescapsuleANDAANDA09059631
PANACEA BIOTEC PHARMA LIMITEDIndiacapsule, gelatin coatedANDAANDA09080231
ASCEND Therapeutics US, LLCcapsuleANDAANDA20374030
Amneal Pharmaceuticals NY LLCcapsule, extended releaseANDAANDA21501230
Jubilant Cadista Pharmaceuticals Inc.capsule, gelatin coatedANDAANDA09080230
MAJOR Pharmaceuticals Inc.capsuleANDAANDA090509, ANDA09068730
Mylan Pharmaceuticals, Inc.capsuleANDAANDA09059630
MylanInstitutional Inc.capsuleANDAANDA09059630
Northstar Rx, LLC,capsuleANDAANDA20666230
Quallent Pharmaceuticals Health, LLCcapsuleANDAANDA09050930
Stellon Biotech Inc.capsuleANDAANDA21311230
Veloxis Pharmaceuticals, Inctablet, extended releaseNDANDA20640630
Cardinal Health 418, Inc.United StatescapsuleANDAANDA090687, ANDA212297234
International Medication Systems, Ltd.United StatescapsuleANDAANDA065461, ANDA20666223
Hangzhou Zhongmei Huadong Pharmaceutical Co., LtdChinacapsuleANDAANDA21092922
Padagis Israel Pharmaceuticals LtdUnited StatesointmentNDANDA05077722
AvPAKcapsuleANDAANDA09050920
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLCointmentANDAANDA20074420
Direct RxUnited StatescapsuleANDAANDA06546111
Nexus Pharmaceuticals, LLCUnited StatesinjectionANDAANDA21710811
Proficient Rx LPUnited StatescapsuleANDAANDA06546111
Aphena Pharma Solutions - Tennessee, LLCcapsuleANDAANDA09059610

Bulk ingredient listings

Orange Book patents

10 unexpired patents list tacrolimus as the active ingredient, expiring between May 2028 and Aug 2028. Application holder: VELOXIS PHARMACEUTICALS INC.

Enquiry

Common questions

Who makes tacrolimus?
35 companies list tacrolimus as a human prescription drug in the openFDA NDC Directory, led by Astellas Pharma US, Inc., Bryant Ranch Prepack, Glenmark Pharmaceuticals Inc., USA, ACCORD HEALTHCARE LIMITED, Dr. Reddy's Laboratories Limited. Each is the labeller, the firm named on the label; the product may be made at a site registered to another company.
Is there a generic Envarsus XR?
32 companies list tacrolimus under an abbreviated new drug application (ANDA), the application type used for generics, and 3 under an NDA or BLA. Listing status is from the NDC Directory; it is not a statement of availability.
Who supplies tacrolimus active ingredient?
18 companies list tacrolimus as a bulk ingredient, including Concord Biotech Limited, Biocon Biologics Limited, Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd, AX Pharmaceutical Corp.