Shortages x suppliers

Shortages, and who else makes them

45 drugs in current FDA shortage, each set against the number of companies that list the same ingredient. 10 have five labellers or fewer. Fewest first.

Shortage records from the FDA drug shortage database; labeller counts from the openFDA NDC Directory (active human prescription listings, every strength and form). A labeller is the firm named on the label and a count is not a statement of stock or supply. Methodology

Matched to the NDC Directory

45 drugs, fewest labellers first

DrugCompanies listing itShortage recordsFirms reportingLast FDA update
penicillin g benzathine24221 Sept 2026
remifentanil hydrochloride39318 Sept 2026
hydroxocobalamin3221 Oct 2026
valproate sodium32218 Sept 2026
meperidine hydrochloride410222 Sept 2026
ifosfamide49418 Sept 2026
fentanyl citrate519322 Sept 2026
dobutamine516322 Sept 2026
sodium acetate51551 Oct 2026
methotrexate sodium514522 Sept 2026
sterile water612522 Sept 2026
dopamine hydrochloride713322 Sept 2026
riluzole74115 Sept 2026
methylprednisolone acetate923521 Sept 2026
quinapril915415 Sept 2026
cromolyn sodium96430 Sept 2026
dextrose monohydrate11571322 Sept 2026
carboplatin1129822 Sept 2026
liraglutide119322 Sept 2026
etomidate1218622 Sept 2026
rifampin1312518 Sept 2026
hydromorphone hydrochloride1726422 Sept 2026
lisdexamfetamine dimesylate181101618 Sept 2026
ropivacaine hydrochloride1949517 Sept 2026
sodium bicarbonate201551 Oct 2026
azacitidine219929 Sept 2026
rocuronium bromide23261122 Sept 2026
heparin sodium2310422 Sept 2026
midazolam hydrochloride2427622 Sept 2026
dexamethasone sodium phosphate2419518 Sept 2026
bupivacaine hydrochloride2560822 Sept 2026
dexmedetomidine hydrochloride25561621 Sept 2026
morphine sulfate2526522 Sept 2026
atropine sulfate251881 Oct 2026
desmopressin acetate284216 Sept 2026
clonazepam3040616 Sept 2026
clindamycin phosphate3020421 Sept 2026
lorazepam3511422 Sept 2026
methylphenidate hydrochloride4338718 Sept 2026
propranolol hydrochloride432218 Sept 2026
promethazine hydrochloride4410222 Sept 2026
furosemide5930922 Sept 2026
ketorolac tromethamine6128722 Sept 2026
metronidazole624317 Sept 2026
lidocaine hydrochloride80681022 Sept 2026
Not matched

Combinations and single-labeller names

These shortage names are combinations, or have fewer than two labellers in the directory, so they are not counted above rather than matched loosely.

  • Amino Acid Injection16
  • Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet73
  • Bacitracin Ophthalmic Ointment1
  • Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection20
  • Cefotaxime Sodium Powder, for Solution6
  • Conivaptan Hydrochloride Injection1
  • Echothiophate Iodide Ophthalmic Solution1
  • Epinephrine Bitartrate, Lidocaine Hydrochloride Injection23
  • Flurazepam Hydrochloride Capsule6
  • Isocarboxazid Tablet1
  • Pentostatin Injection1
  • Quinapril/Hydrochlorothiazide Tablet9
  • Sterile Water Irrigant9
  • Streptozocin Powder, For Solution2
  • Sufentanil Citrate Injection4
  • Technetium TC-99M Pyrophosphate Kit Injection3
  • Triamcinolone Hexacetonide Injection1
For buyers and suppliers

Sourcing a drug that is short?

Send one brief and it goes to FDA-registered suppliers whose registrations match. Suppliers with capacity in a shortage molecule can claim their entry for free.

Enquiry

Common questions

Which drugs in shortage have the fewest manufacturers?
Of the 45 drugs in current FDA shortage that match an ingredient in the NDC Directory, 10 are listed by five companies or fewer, including penicillin g benzathine (2), remifentanil hydrochloride (3), hydroxocobalamin (3), valproate sodium (3). A listing names the labeller on the product; it does not show that the firm has stock.
How many companies make a typical drug in shortage?
The median drug in current shortage is listed by 18 companies in the NDC Directory. The count includes every labeller with an active human prescription listing for the ingredient, across all strengths and dosage forms.
Provenance

FDA drug shortage database (current records, refreshed daily) joined to the openFDA NDC Directory by ingredient name, dropping only dosage-form words and strengths from the shortage name. Combinations are never split into their parts.