| Brand | Active ingredient | Application holder | Expiry | Excl. |
|---|---|---|---|---|
| ABILIFY | ARIPIPRAZOLE | OTSUKA PHARMACEUTICAL CO LTD | 28 Jul | - |
| ABILIFY MYCITE KIT | ARIPIPRAZOLE | OTSUKA PHARMACEUTICAL CO LTD | 28 Apr | - |
| ABILIFY MYCITE KIT | ARIPIPRAZOLE | OTSUKA PHARMACEUTICAL CO LTD | 28 Jul | - |
| ABILIFY MYCITE KIT | ARIPIPRAZOLE | OTSUKA PHARMACEUTICAL CO LTD | 14 Sept | - |
| ABRAXANE | PACLITAXEL | BRISTOL-MYERS SQUIBB CO | 21 Feb | - |
| ABRAXANE | PACLITAXEL | BRISTOL-MYERS SQUIBB CO | 13 Aug | - |
| ABRAXANE | PACLITAXEL | BRISTOL-MYERS SQUIBB CO | 21 Aug | - |
| ACETADOTE | ACETYLCYSTEINE | APOTEX INC | 21 May | D-196 |
| ACTOPLUS MET XR | METFORMIN HYDROCHLORIDE; PIOGLITAZONE HYDROCHLORIDE | TAKEDA PHARMACEUTICALS USA INC | 31 Jul | - |
| ADASUVE | LOXAPINE | NOVA PNEUMA INC | 23 Oct | - |
| ADEMPAS | RIOCIGUAT | BAYER HEALTHCARE PHARMACEUTICALS INC | 04 Dec | - |
| ADZENYS XR-ODT | AMPHETAMINE | NEOS THERAPEUTICS | 09 Apr | - |
| AFINITOR | EVEROLIMUS | NOVARTIS PHARMACEUTICALS CORP | 01 May | - |
| AKTEN | LIDOCAINE HYDROCHLORIDE | THEA PHARMA INC | 24 Jul | - |
| ALYFTREK | DEUTIVACAFTOR; TEZACAFTOR; VANZACAFTOR CALCIUM | VERTEX PHARMACEUTICALS INC | 06 Jul | ODE-536 |
| ALYFTREK | DEUTIVACAFTOR; TEZACAFTOR; VANZACAFTOR CALCIUM | VERTEX PHARMACEUTICALS INC | 28 Dec | ODE-536 |
| ANDROGEL | TESTOSTERONE | BESINS HEALTHCARE IRELAND LTD | 12 Oct | - |
| APLENZIN | BUPROPION HYDROBROMIDE | BAUSCH HEALTH US LLC | 27 Jun | - |
| APRETUDE | CABOTEGRAVIR | VIIV HEALTHCARE CO | 28 Apr | NCE |
| APTIOM | ESLICARBAZEPINE ACETATE | SUMITOMO PHARMA AMERICA INC | 21 Apr | - |
| ARICEPT | DONEPEZIL HYDROCHLORIDE | EISAI INC | 04 Oct | - |
| ARIKAYCE KIT | AMIKACIN SULFATE | INSMED INC | 05 Dec | GAIN |
| ATELVIA | RISEDRONATE SODIUM | ALLERGAN PHARMACEUTICALS INTERNATIONAL LTD | 16 Jan | - |
| ATRIPLA | EFAVIRENZ; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE | GILEAD SCIENCES LLC | 13 Jun | - |
| AUBAGIO | TERIFLUNOMIDE | SANOFI AVENTIS US LLC | 12 Sept | - |
| AURYXIA | FERRIC CITRATE | KERYX BIOPHARMACEUTICALS INC | 21 Apr | - |
| AUVI-Q | EPINEPHRINE | KALEO INC | 12 Dec | - |
| AVYCAZ | AVIBACTAM SODIUM; CEFTAZIDIME | ABBVIE INC | 07 Jan | NPP |
| AVYCAZ | AVIBACTAM SODIUM; CEFTAZIDIME | ABBVIE INC | 12 Nov | NPP |
| AXIRON | TESTOSTERONE | ELI LILLY AND CO | 02 Jun | - |
| AXUMIN | FLUCICLOVINE F-18 | BLUE EARTH DIAGNOSTICS LTD | 28 Nov | - |
| AZILECT | RASAGILINE MESYLATE | TEVA NEUROSCIENCE INC | 05 Dec | - |
| BAXDELA | DELAFLOXACIN MEGLUMINE | MELINTA SUBSIDIARY CORP | 06 Aug | GAIN |
| BAXDELA | DELAFLOXACIN MEGLUMINE | MELINTA SUBSIDIARY CORP | 02 Oct | GAIN |
| BELEODAQ | BELINOSTAT | ACROTECH BIOPHARMA INC | 10 Aug | - |
| BELRAPZO | BENDAMUSTINE HYDROCHLORIDE | EAGLE PHARMACEUTICALS INC | 12 Jan | - |
| BENDEKA | BENDAMUSTINE HYDROCHLORIDE | EAGLE PHARMACEUTICALS INC | 12 Jan | - |
| BEVYXXA | BETRIXABAN | PORTOLA PHARMACEUTICALS INC | 07 Nov | - |
| BEVYXXA | BETRIXABAN | PORTOLA PHARMACEUTICALS INC | 08 Nov | - |
| BOSULIF | BOSUTINIB MONOHYDRATE | PF PRISM CV | 11 Jun | PED |
| BOSULIF | BOSUTINIB MONOHYDRATE | PF PRISM CV | 23 Nov | PED |
| BRIDION | SUGAMMADEX SODIUM | MERCK SHARP AND DOHME LLC A SUB OF MERCK AND CO INC | 27 Jan | PED |
| BRIDION | SUGAMMADEX SODIUM | MERCK SHARP AND DOHME LLC A SUB OF MERCK AND CO INC | 27 Jul | PED |
| BRISDELLE | PAROXETINE MESYLATE | LEGACY PHARMA INC SEZC | 04 Aug | - |
| BRIVIACT | BRIVARACETAM | UCB INC | 21 Feb | - |
| BRIXADI | BUPRENORPHINE | BRAEBURN INC | 31 Jul | NP |
| BYDUREON | EXENATIDE SYNTHETIC | ASTRAZENECA AB | 04 Apr | - |
| BYDUREON | EXENATIDE SYNTHETIC | ASTRAZENECA AB | 18 Aug | - |
| BYDUREON BCISE | EXENATIDE SYNTHETIC | ASTRAZENECA AB | 04 Apr | - |
| BYDUREON BCISE | EXENATIDE SYNTHETIC | ASTRAZENECA AB | 18 Aug | - |
| BYDUREON PEN | EXENATIDE SYNTHETIC | ASTRAZENECA AB | 04 Apr | - |
| BYDUREON PEN | EXENATIDE SYNTHETIC | ASTRAZENECA AB | 18 Aug | - |
| BYVALSON | NEBIVOLOL HYDROCHLORIDE; VALSARTAN | ABBVIE INC | 29 Aug | - |
| CABENUVA KIT | CABOTEGRAVIR; RILPIVIRINE | VIIV HEALTHCARE CO | 28 Apr | NCE |
| CABOMETYX | CABOZANTINIB S-MALATE | EXELIXIS INC | 14 Aug | ODE-530 |
| CALQUENCE | ACALABRUTINIB MALEATE | ASTRAZENECA UK LTD | 24 Nov | D-200 |
| CAMBIA | DICLOFENAC POTASSIUM | COSETTE PHARMACEUTICALS INC | 16 Jun | - |
| CERDELGA | ELIGLUSTAT TARTRATE | GENZYME CORP | 26 Jun | - |
| CHLORHEXIDINE GLUCONATE | CHLORHEXIDINE GLUCONATE | SAGE PRODUCTS INC | 25 Apr | - |
| CLINDESSE | CLINDAMYCIN PHOSPHATE | PADAGIS US LLC | 02 Dec | - |
| CLOROTEKAL | CHLOROPROCAINE HYDROCHLORIDE | B BRAUN MEDICAL INC | 05 Sept | - |
| COLAZAL | BALSALAZIDE DISODIUM | VALEANT PHARMACEUTICALS INTERNATIONAL | 24 Aug | - |
| COMETRIQ | CABOZANTINIB S-MALATE | EXELIXIS INC | 14 Aug | - |
| COREG CR | CARVEDILOL PHOSPHATE | WAYLIS THERAPEUTICS LLC | 11 Mar | - |
| CORLANOR | IVABRADINE | AMGEN INC | 22 Feb | PED |
| CORLANOR | IVABRADINE HYDROCHLORIDE | AMGEN INC | 22 Aug | - |
| CORLANOR | IVABRADINE HYDROCHLORIDE | AMGEN INC | 12 Dec | - |
| COTELLIC | COBIMETINIB FUMARATE | GENENTECH INC | 05 Oct | ODE-416 |
| COTEMPLA XR-ODT | METHYLPHENIDATE | NEOS THERAPEUTICS INC | 05 Jun | - |
| CRESEMBA | ISAVUCONAZONIUM SULFATE | ASTELLAS PHARMA US INC | 30 Apr | PED |
| DEFENCATH | HEPARIN SODIUM; TAUROLIDINE | CORMEDIX INC | 16 May | GAIN |
| DEXILANT | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 17 Jan | - |
| DEXILANT | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 24 Feb | - |
| DEXILANT | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 17 Jul | - |
| DEXILANT | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 02 Aug | - |
| DEXILANT | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 27 Sept | - |
| DEXILANT SOLUTAB | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 17 Jan | - |
| DEXILANT SOLUTAB | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 24 Feb | - |
| DEXILANT SOLUTAB | DEXLANSOPRAZOLE | TAKEDA PHARMACEUTICALS USA INC | 17 Jul | - |
| DIFFERIN | ADAPALENE | GALDERMA LABORATORIES LP | 15 Sept | - |
| DUEXIS | FAMOTIDINE; IBUPROFEN | HORIZON MEDICINES LLC | 18 Jul | - |
| DURYSTA | BIMATOPROST | ABBVIE INC | 19 Dec | - |
| DYMISTA | AZELASTINE HYDROCHLORIDE; FLUTICASONE PROPIONATE | MYLAN SPECIALTY LP | 24 Feb | - |
| DYMISTA | AZELASTINE HYDROCHLORIDE; FLUTICASONE PROPIONATE | MYLAN SPECIALTY LP | 24 Aug | - |
| ELEPSIA XR | LEVETIRACETAM | TRIPOINT THERAPEUTICS | 22 Feb | - |
| ELIQUIS | APIXABAN | BRISTOL MYERS SQUIBB CO PHARMACEUTICAL RESEARCH INSTITUTE | 21 Nov | PED |
| ELIQUIS SPRINKLE | APIXABAN | BRISTOL MYERS SQUIBB CO | 21 Nov | PED |
| EMBLAVEO | AVIBACTAM SODIUM; AZTREONAM | ABBVIE INC | 07 Jan | GAIN |
| EMBLAVEO | AVIBACTAM SODIUM; AZTREONAM | ABBVIE INC | 12 Nov | GAIN |
| ENTRESTO | SACUBITRIL; VALSARTAN | NOVARTIS PHARMACEUTICALS CORP | 08 Nov | - |
| ENTRESTO SPRINKLE | SACUBITRIL; VALSARTAN | NOVARTIS PHARMACEUTICALS CORP | 08 Nov | - |
| EOHILIA | BUDESONIDE | TAKEDA PHARMACEUTICALS USA INC | 09 Nov | ODE-466 |
| EPANOVA | OMEGA-3-CARBOXYLIC ACIDS | ASTRAZENECA PHARMACEUTICALS LP | 20 Dec | - |
| ESBRIET | PIRFENIDONE | LEGACY PHARMA INC SEZC | 22 Sept | - |
| EVZIO | NALOXONE HYDROCHLORIDE | KALEO INC | 01 Feb | - |
| EVZIO | NALOXONE HYDROCHLORIDE | KALEO INC | 31 Mar | - |
| EVZIO | NALOXONE HYDROCHLORIDE | KALEO INC | 10 Jun | - |
| EVZIO | NALOXONE HYDROCHLORIDE | KALEO INC | 25 Jun | - |
| EVZIO | NALOXONE HYDROCHLORIDE | KALEO INC | 12 Dec | - |
| EVZIO (AUTOINJECTOR) | NALOXONE HYDROCHLORIDE | KALEO INC | 01 Feb | - |
| EVZIO (AUTOINJECTOR) | NALOXONE HYDROCHLORIDE | KALEO INC | 31 Mar | - |
| EVZIO (AUTOINJECTOR) | NALOXONE HYDROCHLORIDE | KALEO INC | 01 Jun | - |
| EVZIO (AUTOINJECTOR) | NALOXONE HYDROCHLORIDE | KALEO INC | 25 Jun | - |
| EVZIO (AUTOINJECTOR) | NALOXONE HYDROCHLORIDE | KALEO INC | 12 Dec | - |
| FARXIGA | DAPAGLIFLOZIN | ASTRAZENECA AB | 04 Apr | PED |
| FARXIGA | DAPAGLIFLOZIN | ASTRAZENECA AB | 18 Aug | PED |
| FETZIMA | LEVOMILNACIPRAN HYDROCHLORIDE | ABBVIE INC | 11 Jan | M-304 |
| FLONASE SENSIMIST ALLERGY RELIEF | FLUTICASONE FUROATE | HALEON US HOLDINGS LLC | 05 Apr | - |
| FLYRCADO | FLURPIRIDAZ F-18 | GE HEALTHCARE INC | 04 Feb | NCE |
| FLYRCADO | FLURPIRIDAZ F-18 | GE HEALTHCARE INC | 26 May | NCE |
| FYCOMPA | PERAMPANEL | CATALYST PHARMACEUTICALS INC | 01 Jul | - |
| GATTEX KIT | TEDUGLUTIDE | TAKEDA PHARMACEUTICALS USA INC | 01 May | ODE-240 |
| GENOSYL | NITRIC OXIDE | VERO BIOTECH INC | 18 Jan | - |
| GENOSYL | NITRIC OXIDE | VERO BIOTECH INC | 17 Oct | - |
| GENVOYA | COBICISTAT; ELVITEGRAVIR; EMTRICITABINE; TENOFOVIR ALAFENAMIDE FUMARATE | GILEAD SCIENCES INC | 27 Aug | - |
| GENVOYA | COBICISTAT; ELVITEGRAVIR; EMTRICITABINE; TENOFOVIR ALAFENAMIDE FUMARATE | GILEAD SCIENCES INC | 26 Oct | - |
| GIAZO | BALSALAZIDE DISODIUM | VALEANT PHARMACEUTICALS INTERNATIONAL | 02 Aug | - |
| GIAZO | BALSALAZIDE DISODIUM | VALEANT PHARMACEUTICALS INTERNATIONAL | 24 Aug | - |
| GILOTRIF | AFATINIB DIMALEATE | BOEHRINGER INGELHEIM | 13 Jan | - |
| GILOTRIF | AFATINIB DIMALEATE | BOEHRINGER INGELHEIM | 13 Jul | - |
| GILOTRIF | AFATINIB DIMALEATE | BOEHRINGER INGELHEIM | 09 Nov | - |
| GLYXAMBI | EMPAGLIFLOZIN; LINAGLIPTIN | BOEHRINGER INGELHEIM | 26 May | - |
| GRAFAPEX | TREOSULFAN | MEDEXUS PHARMA INC | 12 Oct | ODE-513 |
| HERNEXEOS | ZONGERTINIB | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 15 Nov | NCE |
| HORIZANT | GABAPENTIN ENACARBIL | AZURITY PHARMACEUTICALS INC | 11 Apr | - |
| HORIZANT | GABAPENTIN ENACARBIL | AZURITY PHARMACEUTICALS INC | 10 Nov | - |
| ICLUSIG | PONATINIB HYDROCHLORIDE | TAKEDA PHARMACEUTICALS USA INC | 22 Dec | ODE-472 |
| IMBRUVICA | IBRUTINIB | PHARMACYCLICS LLC | 28 Dec | PED |
| INREBIC | FEDRATINIB HYDROCHLORIDE | BRISTOL-MYERS SQUIBB CO | 16 Dec | ODE-259 |
| ISTURISA | OSILODROSTAT PHOSPHATE | RECORDATI RARE DISEASES INC | 23 Aug | ODE-535 |
| IZERVAY | AVACINCAPTAD PEGOL SODIUM | ASTELLAS PHARMA US INC | 11 Nov | - |
| JAKAFI | RUXOLITINIB PHOSPHATE | INCYTE CORP | 12 Dec | PED |
| JAKAFI XR | RUXOLITINIB PHOSPHATE | INCYTE CORP | 12 Dec | PED |
| JANUMET | METFORMIN HYDROCHLORIDE; SITAGLIPTIN PHOSPHATE | MERCK SHARP AND DOHME LLC A SUB OF MERCK AND CO INC | 24 Nov | - |
| JANUMET XR | METFORMIN HYDROCHLORIDE; SITAGLIPTIN PHOSPHATE | MERCK SHARP AND DOHME LLC A SUB OF MERCK AND CO INC | 24 Nov | - |
| JANUVIA | SITAGLIPTIN PHOSPHATE | MERCK SHARP AND DOHME LLC | 24 Nov | - |
| JATENZO | TESTOSTERONE UNDECANOATE | TOLMAR INC | 14 Apr | - |
| JENTADUETO | LINAGLIPTIN; METFORMIN HYDROCHLORIDE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 26 May | PED |
| JENTADUETO XR | LINAGLIPTIN; METFORMIN HYDROCHLORIDE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 26 May | PED |
| JEVTANA KIT | CABAZITAXEL | SANOFI AVENTIS US INC | 10 Jun | - |
| JUBLIA | EFINACONAZOLE | BAUSCH HEALTH AMERICAS INC | 22 Feb | - |
| JUVISYNC | SIMVASTATIN; SITAGLIPTIN PHOSPHATE | MERCK SHARP AND DOHME CORP | 11 Apr | - |
| JUVISYNC | SIMVASTATIN; SITAGLIPTIN PHOSPHATE | MERCK SHARP AND DOHME CORP | 11 Oct | - |
| JYNARQUE | TOLVAPTAN | OTSUKA PHARMACEUTICAL CO LTD | 01 Sept | - |
| KALYDECO | IVACAFTOR | VERTEX PHARMACEUTICALS INC | 06 Jul | PED |
| KALYDECO | IVACAFTOR | VERTEX PHARMACEUTICALS INC | 28 Dec | PED |
| KOSELUGO | SELUMETINIB SULFATE | ASTRAZENECA PHARMACEUTICALS LP | 13 Mar | ODE* |
| KOSELUGO | SELUMETINIB SULFATE | ASTRAZENECA PHARMACEUTICALS LP | 12 Dec | ODE-545 |
| KUVAN | SAPROPTERIN DIHYDROCHLORIDE | BIOMARIN PHARMACEUTICAL INC | 16 May | - |
| KYPROLIS | CARFILZOMIB | ONYX PHARMACEUTICALS INC A WHOLLY OWNED SUB OF AMGEN INC | 20 Jul | PED |
| LATUDA | LURASIDONE HYDROCHLORIDE | SUNOVION PHARMACEUTICALS INC | 26 May | - |
| LATUDA | LURASIDONE HYDROCHLORIDE | SUNOVION PHARMACEUTICALS INC | 26 Nov | - |
| LENVIMA | LENVATINIB MESYLATE | EISAI INC | 24 Apr | PED |
| LENVIMA | LENVATINIB MESYLATE | EISAI INC | 19 Sept | PED |
| LINZESS | LINACLOTIDE | ABBVIE INC | 30 Aug | - |
| LIVDELZI | SELADELPAR LYSINE | GILEAD SCIENCES INC | 02 Aug | ODE-486 |
| LIVDELZI | SELADELPAR LYSINE | GILEAD SCIENCES INC | 13 Sept | ODE-486 |
| LONHALA MAGNAIR KIT | GLYCOPYRROLATE | SUMITOMO PHARMA AMERICA INC | 16 Aug | - |
| LYRICA CR | PREGABALIN | UPJOHN US 2 LLC | 02 Nov | - |
| MITOSOL | MITOMYCIN | GLAUKOS CORP | 19 Jul | - |
| MOXATAG | AMOXICILLIN | PRAGMA PHARMACEUTICALS LLC | 08 Dec | - |
| MYDAYIS | AMPHETAMINE ASPARTATE; AMPHETAMINE SULFATE; DEXTROAMPHETAMINE SACCHARATE; DEXTROAMPHETAMINE SULFATE | TAKEDA PHARMACEUTICALS USA INC | 12 May | - |
| MYFEMBREE | ESTRADIOL; NORETHINDRONE ACETATE; RELUGOLIX | SUMITOMO PHARMA AMERICA INC | 28 Jan | M-289 |
| NAPROXEN SODIUM | NAPROXEN SODIUM | BIONPHARMA INC | 03 Mar | - |
| NAROPIN | ROPIVACAINE HYDROCHLORIDE | FRESENIUS KABI USA LLC | 28 Nov | - |
| NATAZIA | DIENOGEST; ESTRADIOL VALERATE | BAYER HEALTHCARE PHARMACEUTICALS INC | 13 May | - |
| NEXPLANON | ETONOGESTREL | ORGANON USA LLC | 28 Aug | D-199 |
| NUEDEXTA | DEXTROMETHORPHAN HYDROBROMIDE; QUINIDINE SULFATE | OTSUKA AMERICA PHARMACEUTICAL INC | 13 Aug | - |
| NUPLAZID | PIMAVANSERIN TARTRATE | ACADIA PHARMACEUTICALS INC | 24 Aug | PED |
| OFEV | NINTEDANIB ESYLATE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 08 Jan | PED |
| OFEV | NINTEDANIB ESYLATE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 01 Apr | PED |
| OFEV | NINTEDANIB ESYLATE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 08 Jul | PED |
| OLYSIO | SIMEPREVIR SODIUM | JANSSEN PRODUCTS LP | 28 Jul | - |
| OMEGAVEN | FISH OIL TRIGLYCERIDES | FRESENIUS KABI USA LLC | 30 Jul | - |
| OMONTYS | PEGINESATIDE ACETATE | TAKEDA PHARMACEUTICALS USA INC | 02 Jun | - |
| OMONTYS PRESERVATIVE FREE | PEGINESATIDE ACETATE | TAKEDA PHARMACEUTICALS USA INC | 02 Jun | - |
| ONGENTYS | OPICAPONE | AMNEAL PHARMACEUTICALS LLC | 26 Jul | - |
| ONZETRA XSAIL | SUMATRIPTAN SUCCINATE | AZURITY PHARMACEUTICALS INC | 23 Feb | - |
| OPSUMIT | MACITENTAN | ACTELION PHARMACEUTICALS US INC | 05 Jun | PED |
| OPSUMIT | MACITENTAN | ACTELION PHARMACEUTICALS US INC | 11 Sept | PED |
| OPSYNVI | MACITENTAN; TADALAFIL | ACTELION PHARMACEUTICALS US INC | 05 Jun | PED |
| OPSYNVI | MACITENTAN; TADALAFIL | ACTELION PHARMACEUTICALS US INC | 11 Sept | PED |
| OPZELURA | RUXOLITINIB PHOSPHATE | INCYTE CORP | 12 Dec | NPP |
| ORENITRAM | TREPROSTINIL DIOLAMINE | UNITED THERAPEUTICS CORP | 27 Apr | ODE-272 |
| ORENITRAM | TREPROSTINIL DIOLAMINE | UNITED THERAPEUTICS CORP | 30 Jul | ODE-272 |
| ORGOVYX | RELUGOLIX | SUMITOMO PHARMA AMERICA INC | 28 Jan | - |
| ORKAMBI | IVACAFTOR; LUMACAFTOR | VERTEX PHARMACEUTICALS INC | 08 Nov | PED |
| ORKAMBI | IVACAFTOR; LUMACAFTOR | VERTEX PHARMACEUTICALS INC | 28 Dec | PED |
| ORSERDU | ELACESTRANT HYDROCHLORIDE | STEMLINE THERAPEUTICS INC | 18 Aug | NCE |
| OSPHENA | OSPEMIFENE | DUCHESNAY INC | 11 Aug | - |
| OTREXUP | METHOTREXATE | COSETTE PHARMACEUTICALS INC | 24 Jan | - |
| OTREXUP | METHOTREXATE | COSETTE PHARMACEUTICALS INC | 04 Oct | - |
| OVIDE | MALATHION | TARO PHARMACEUTICAL INDUSTRIES LTD | 14 Aug | - |
| OZEMPIC | SEMAGLUTIDE | NOVO NORDISK INC | 20 Mar | I-976 |
| PERSERIS KIT | RISPERIDONE | INDIVIOR INC | 26 Jun | - |
| PERSERIS KIT | RISPERIDONE | INDIVIOR INC | 26 Sept | - |
| PERSERIS KIT | RISPERIDONE | INDIVIOR INC | 05 Nov | - |
| PICATO | INGENOL MEBUTATE | LEO LABORATORIES LTD | 18 Dec | - |
| PRADAXA | DABIGATRAN ETEXILATE MESYLATE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 07 Mar | - |
| PREZCOBIX | COBICISTAT; DARUNAVIR ETHANOLATE | JANSSEN PRODUCTS LP | 26 Dec | - |
| PREZISTA | DARUNAVIR | JANSSEN PRODUCTS LP | 26 Dec | - |
| PRIMATENE MIST | EPINEPHRINE | ARMSTRONG PHARMACEUTICALS INC | 26 Jan | - |
| PROMACTA | ELTROMBOPAG OLAMINE | NOVARTIS PHARMACEUTICALS CORP | 13 Jan | - |
| PROMACTA KIT | ELTROMBOPAG OLAMINE | NOVARTIS PHARMACEUTICALS CORP | 13 Jan | - |
| PROTONIX | PANTOPRAZOLE SODIUM | WYETH PHARMACEUTICALS LLC | 07 Jun | - |
| PROTONIX | PANTOPRAZOLE SODIUM | WYETH PHARMACEUTICALS LLC | 07 Dec | - |
| QTERN | DAPAGLIFLOZIN; SAXAGLIPTIN HYDROCHLORIDE | ASTRAZENECA AB | 04 Apr | - |
| QTERNMET XR | DAPAGLIFLOZIN; METFORMIN HYDROCHLORIDE; SAXAGLIPTIN HYDROCHLORIDE | ASTRAZENECA AB | 04 Apr | - |
| RECORLEV | LEVOKETOCONAZOLE | STRONGBRIDGE DUBLIN LTD | 10 Jan | ODE-385 |
| REXULTI | BREXPIPRAZOLE | OTSUKA PHARMACEUTICAL CO LTD | 12 Apr | M-315 |
| REXULTI | BREXPIPRAZOLE | OTSUKA PHARMACEUTICAL CO LTD | 12 Oct | M-315 |
| RHOPRESSA | NETARSUDIL MESYLATE | ALCON LABORATORIES INC | 11 Jul | - |
| ROCKLATAN | LATANOPROST; NETARSUDIL DIMESYLATE | ALCON LABORATORIES INC | 11 Jul | - |
| RYBELSUS | SEMAGLUTIDE | NOVO NORDISK INC | 20 Mar | I-976 |
| RYTELO | IMETELSTAT SODIUM | GERON CORP | 09 Sept | ODE-482 |
| RYTELO | IMETELSTAT SODIUM | GERON CORP | 27 Dec | ODE-482 |
| SAMSCA | TOLVAPTAN | OTSUKA PHARMACEUTICAL CO LTD | 01 Sept | - |
| SAPHRIS | ASENAPINE MALEATE | ABBVIE INC | 06 Apr | - |
| SAPHRIS | ASENAPINE MALEATE | ABBVIE INC | 06 Oct | - |
| SAXENDA | LIRAGLUTIDE | NOVO NORDISK INC | 13 Feb | - |
| SENSIPAR | CINACALCET HYDROCHLORIDE | AMGEN INC | 22 Sept | - |
| SIGNIFOR | PASIREOTIDE DIASPARTATE | RECORDATI RARE DISEASES INC | 14 Dec | - |
| SIGNIFOR LAR KIT | PASIREOTIDE PAMOATE | RECORDATI RARE DISEASES INC | 25 Oct | - |
| SIGNIFOR LAR KIT | PASIREOTIDE PAMOATE | RECORDATI RARE DISEASES INC | 14 Dec | - |
| SINUVA | MOMETASONE FUROATE | INTERSECT ENT INC | 04 Apr | - |
| SINUVA | MOMETASONE FUROATE | INTERSECT ENT INC | 29 Nov | - |
| SIRTURO | BEDAQUILINE FUMARATE | JANSSEN THERAPEUTICS DIV JANSSEN PRODUCTS LP | 01 Dec | M-306 |
| SKELAXIN | METAXALONE | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT LLC A SUB OF PFIZER INC | 06 Feb | - |
| SOFDRA | SOFPIRONIUM BROMIDE | BOTANIX SB INC | 13 Nov | NCE |
| SORILUX | CALCIPOTRIENE | MAYNE PHARMA LLC | 26 May | - |
| SPIRIVA | TIOTROPIUM BROMIDE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 19 Jan | - |
| SPIRIVA | TIOTROPIUM BROMIDE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 19 Jul | - |
| SPRYCEL | DASATINIB | BRISTOL MYERS SQUIBB CO | 28 Mar | PED |
| SPRYCEL | DASATINIB | BRISTOL MYERS SQUIBB CO | 28 Sept | PED |
| STEGLUJAN | ERTUGLIFLOZIN; SITAGLIPTIN PHOSPHATE | MERCK SHARP AND DOHME LLC A SUB OF MERCK AND CO INC | 24 Nov | - |
| STRIBILD | COBICISTAT; ELVITEGRAVIR; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE | GILEAD SCIENCES INC | 27 Aug | - |
| STRIBILD | COBICISTAT; ELVITEGRAVIR; EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE | GILEAD SCIENCES INC | 26 Oct | - |
| SUMAVEL DOSEPRO | SUMATRIPTAN SUCCINATE | ENDO OPERATIONS LTD | 31 Jul | - |
| SUMAVEL DOSEPRO | SUMATRIPTAN SUCCINATE | ENDO OPERATIONS LTD | 22 Nov | - |
| SUNOSI | SOLRIAMFETOL HYDROCHLORIDE | AXSOME MALTA LTD | 07 Jun | ODE-254 |
| SUPPRELIN LA | HISTRELIN ACETATE | ENDO OPERATIONS LTD | 16 Jun | - |
| SYFOVRE | PEGCETACOPLAN | APELLIS PHARMACEUTICALS INC | 25 Oct | NCE |
| SYMDEKO (COPACKAGED) | IVACAFTOR; IVACAFTOR, TEZACAFTOR | VERTEX PHARMACEUTICALS INC | 06 Jul | ODE-335 |
| SYMDEKO (COPACKAGED) | IVACAFTOR; IVACAFTOR, TEZACAFTOR | VERTEX PHARMACEUTICALS INC | 28 Dec | ODE-335 |
| SYMPROIC | NALDEMEDINE TOSYLATE | BIODELIVERY SCIENCES INTERNATIONAL INC | 05 Oct | - |
| SYMTUZA | COBICISTAT; DARUNAVIR; EMTRICITABINE; TENOFOVIR ALAFENAMIDE FUMARATE | JANSSEN PRODUCTS LP | 26 Dec | - |
| SYNRIBO | OMACETAXINE MEPESUCCINATE | TEVA PHARMACEUTICALS INTERNATIONAL GMBH | 26 Oct | - |
| TASIGNA | NILOTINIB HYDROCHLORIDE | NOVARTIS PHARMACEUTICALS CORP | 18 Jul | PED |
| TAVALISSE | FOSTAMATINIB DISODIUM | RIGEL PHARMACEUTICALS INC | 19 Jan | - |
| TAVALISSE | FOSTAMATINIB DISODIUM | RIGEL PHARMACEUTICALS INC | 28 Mar | - |
| TAVALISSE | FOSTAMATINIB DISODIUM | RIGEL PHARMACEUTICALS INC | 12 Jun | - |
| TAVALISSE | FOSTAMATINIB DISODIUM | RIGEL PHARMACEUTICALS INC | 17 Jun | - |
| TEKTURNA | ALISKIREN HEMIFUMARATE | LXO IRELAND DESIGNATED ACTIVITY CO | 19 Feb | - |
| TEKTURNA | ALISKIREN HEMIFUMARATE | LXO IRELAND DESIGNATED ACTIVITY CO | 19 Aug | - |
| TOPICORT | DESOXIMETASONE | SUN PHARMA CANADA INC | 26 May | - |
| TORISEL | TEMSIROLIMUS | PF PRISM CV | 20 Jan | - |
| TORISEL | TEMSIROLIMUS | PF PRISM CV | 20 Jul | - |
| TOSYMRA | SUMATRIPTAN | TONIX MEDICINES INC | 09 May | - |
| TRACLEER | BOSENTAN | ACTELION PHARMACEUTICALS US INC | 15 May | - |
| TRADJENTA | LINAGLIPTIN | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 26 May | PED |
| TREANDA | BENDAMUSTINE HYDROCHLORIDE | CEPHALON INC | 12 Jan | - |
| TREANDA | BENDAMUSTINE HYDROCHLORIDE | CEPHALON INC | 12 Jul | - |
| TREXIMET | NAPROXEN SODIUM; SUMATRIPTAN SUCCINATE | AZURITY PHARMACEUTICALS INC | 02 Apr | - |
| TRIJARDY XR | EMPAGLIFLOZIN; LINAGLIPTIN; METFORMIN HYDROCHLORIDE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC | 26 May | - |
| TRIKAFTA (COPACKAGED) | ELEXACAFTOR, IVACAFTOR, TEZACAFTOR; IVACAFTOR | VERTEX PHARMACEUTICALS INC | 06 Jul | ODE-543 |
| TRIKAFTA (COPACKAGED) | ELEXACAFTOR, IVACAFTOR, TEZACAFTOR; IVACAFTOR | VERTEX PHARMACEUTICALS INC | 28 Dec | ODE-543 |
| TRINTELLIX | VORTIOXETINE HYDROBROMIDE | TAKEDA PHARMACEUTICALS USA INC | 17 Jun | PED |
| TRINTELLIX | VORTIOXETINE HYDROBROMIDE | TAKEDA PHARMACEUTICALS USA INC | 17 Dec | PED |
| TYGACIL | TIGECYCLINE | PF PRISM CV | 13 Mar | - |
| UPTRAVI | SELEXIPAG | ACTELION PHARMACEUTICALS US INC | 31 Oct | PED |
| VALCHLOR | MECHLORETHAMINE HYDROCHLORIDE | HELSINN BIREX PHARMACEUTICALS LTD | 07 Mar | - |
| VALTURNA | ALISKIREN HEMIFUMARATE; VALSARTAN | NOVARTIS PHARMACEUTICALS CORP | 03 Jul | - |
| VEREGEN | SINECATECHINS | ANI PHARMACEUTICALS INC | 02 Oct | - |
| VERKAZIA | CYCLOSPORINE | HARROW EYE LLC | 27 Jan | ODE-358 |
| VICTOZA | LIRAGLUTIDE | NOVO NORDISK INC | 13 Feb | - |
| VITEKTA | ELVITEGRAVIR | GILEAD SCIENCES INC | 27 Aug | - |
| VITEKTA | ELVITEGRAVIR | GILEAD SCIENCES INC | 26 Oct | - |
| VIZIMPRO | DACOMITINIB | PFIZER INC | 02 Feb | - |
| VOCABRIA | CABOTEGRAVIR SODIUM | VIIV HEALTHCARE CO | 28 Apr | NCE |
| VYKAT XR | DIAZOXIDE CHOLINE | SOLENO THERAPEUTICS INC | 20 Dec | ODE-532 |
| VYNDAMAX | TAFAMIDIS | FOLDRX PHARMACEUTICALS LLC A WHOLLY OWNED SUB OF PFIZER INC | 19 Dec | ODE-237 |
| VYNDAQEL | TAFAMIDIS MEGLUMINE | FOLDRX PHARMACEUTICALS LLC A WHOLLY OWNED SUB OF PFIZER INC | 19 Dec | ODE-237 |
| VYXEOS | CYTARABINE; DAUNORUBICIN | JAZZ PHARMACEUTICALS THERAPEUTICS INC | 07 Jun | PED |
| WAINUA (AUTOINJECTOR) | EPLONTERSEN SODIUM | ASTRAZENECA AB | 01 Apr | ODE-461 |
| WAKIX | PITOLISANT HYDROCHLORIDE | HARMONY BIOSCIENCES MANAGEMENT INC | 06 Feb | ODE-519 |
| WEGOVY | SEMAGLUTIDE | NOVO NORDISK INC | 20 Mar | I-973 |
| XEGLYZE | ABAMETAPIR | LNHC INC | 28 Oct | - |
| XELJANZ | TOFACITINIB CITRATE | PF PRISM CV | 08 Jun | PED |
| XELJANZ XR | TOFACITINIB CITRATE | PFIZER INC | 08 Jun | - |
| XIFAXAN | RIFAXIMIN | SALIX PHARMACEUTICALS INC | 27 Feb | - |
| XIGDUO XR | DAPAGLIFLOZIN; METFORMIN HYDROCHLORIDE | ASTRAZENECA AB | 04 Apr | PED |
| XIIDRA | LIFITEGRAST | BAUSCH AND LOMB INC | 17 May | - |
| XTANDI | ENZALUTAMIDE | ASTELLAS PHARMA US INC | 15 May | I-926 |
| XTANDI | ENZALUTAMIDE | ASTELLAS PHARMA US INC | 24 Aug | I-926 |
| XYOSTED (AUTOINJECTOR) | TESTOSTERONE ENANTHATE | ANTARES PHARMA INC | 24 Jan | - |
| XYOSTED (AUTOINJECTOR) | TESTOSTERONE ENANTHATE | ANTARES PHARMA INC | 04 Oct | - |
| ZELBORAF | VEMURAFENIB | HOFFMANN LA ROCHE INC | 21 Jun | - |
| ZELBORAF | VEMURAFENIB | HOFFMANN LA ROCHE INC | 02 Aug | - |
| ZELBORAF | VEMURAFENIB | HOFFMANN LA ROCHE INC | 22 Oct | - |
| ZELSUVMI | BERDAZIMER SODIUM | LNHC INC | 30 May | NCE |
| ZETIA | EZETIMIBE | ORGANON LLC A SUB OF ORGANON AND CO | 30 Apr | - |
| ZOLINZA | VORINOSTAT | MERCK SHARP AND DOHME LLC A SUB OF MERCK AND CO INC | 16 May | - |
| ZTALMY | GANAXOLONE | IMMEDICA PHARMA AB | 28 Nov | ODE-395 |
| ZUNVEYL | BENZGALANTAMINE GLUCONATE | ALPHA COGNITION INC | 01 Dec | - |
| ZYKADIA | CERITINIB | NOVARTIS PHARMACEUTICALS CORP | 25 Apr | - |
Provenance
Source: FDA Orange Book patent and exclusivity files. Rows carrying an exclusivity code have a separate regulatory exclusivity that can outlast the patent shown. Patent expiry alone does not determine when a generic can launch: paediatric extensions, 30-month stays and settlement agreements frequently move the effective date. Delisted patents are excluded.